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Goodman & Gilman's The Pharmacological Basis of Therapeutics, 11e
5/29/2008: Pharmacogenetics of Thiopurines
Iulia Oancea
Postgraduate Fellow, Mater Medical Research Institute, Brisbane, Australia
John A. Duley
Senior Scientist, Mater Hospital, and Senior Lecturer, University of Queensland, Brisbane, Australia
Topics Discussed: 5,10-methylenetetrahydrofolate reductase; 6-mercaptopurine; allopurinol; azathioprine; chemistry of antineoplastic agents; drug metabolism; drug response; folic acid; glutathione s-transferase; inflammatory bowel disease; irritable bowel syndrome; leukemia; pharmacogenetics; pharmacogenetics of phase ii drug metabolism; n-acetyltransferase, glutathione transferase, sulfotransferases, catechol-o-methyltransferase, thiopurine methyltransferase; pharmacogenomics; pharmacotherapy of gastrointestinal disorders; pharmacotherapy of oncologic disorders; purine nucleosides; s-adenosylmethionine; thioguanine; thiopurine; tpmt gene; xanthine oxidase.
Related to Chapter 3. Drug Metabolism; Chapter 38. Pharmacotherapy of Inflammatory Bowel Disease; Chapter 4. Pharmacogenetics; Chapter 51. Antineoplastic Agents; View in chapter; Chapter 3, Figure 3-10;
Excerpt:
"View in chapter..."
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