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Harrison's Principles of Internal Medicine, 17e
| Part 2. Cardinal Manifestations and Presentation of Diseases > |
Skin Diseases and Smallpox Vaccination
Sections: Skin Diseases
and Smallpox Vaccination.
Topics Discussed: acne vulgaris; dermatologic drug reactions and self-treatable skin disorders; eczema; psoriasis; skin diseases, infectious; smallpox vaccine; vaccines, toxoids, and other immunobiologics.
Excerpt:
"Given the potential threat of a bioterrorism attack with smallpox, vaccinations against smallpox are available to the general public, although they are not recommended. Because of a higher incidence of adverse events associated with smallpox vaccination in patients with a history of certain skin diseases, including atopic dermatitis, eczema, and psoriasis, such vaccination is contraindicated in patients with these conditions in the absence of a bioterrorism attack and a real or potential exposure to smallpox. In the case of such exposure, the risk of smallpox infection outweighs the risk of adverse events from the vaccine (Chap. 214)...."
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